Ekaterina Zezina, Oezen Sercan‐Alp, Matthias Herrmann, Nadine Biesemann
Published Online: Jun 11 2020
DOI: 10.1002/wsbm.1498
The cover image is based on the Advanced Review Glucose transporter 1 in rheumatoid arthritis and autoimmunity by Ekaterina Zezina et al., https://doi.org/10.1002/wsbm.1483.
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Tilmann Glimm, Ramray Bhat, Stuart A. Newman
Published Online: Mar 24 2020
DOI: 10.1002/wsbm.1485
Drawings (left) and simulations (right) of experimentally manipulated (ZPA graft; chicken) (top), and mutant (Shh‐/‐Gli3‐/‐; mouse) (bottom) embryonic limbs.
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Sahak Z. Makaryan, Colin G. Cess, Stacey D. Finley
Published Online: Mar 04 2020
DOI: 10.1002/wsbm.1484
A better understanding of immune cell response in tumors requires multiscale modeling of intracellular signaling, multicellular interactions, and spatial and whole‐body dynamics.
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Dominic G. Whittaker, Michael Clerx, Chon Lok Lei, David J. Christini, Gary R. Mirams
Published Online: Feb 21 2020
DOI: 10.1002/wsbm.1482
A schematic of a cardiac electrophysiology model, highlighting the components described by equations that need to be calibrated using experimental data.
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Ekaterina Zezina, Oezen Sercan‐Alp, Matthias Herrmann, Nadine Biesemann
Published Online: Feb 21 2020
DOI: 10.1002/wsbm.1483
Increased glucose uptake via the glucose transporter 1 (GLUT1) is essential for immune cell activation and is upregulated in different autoimmune diseases, like rheumatoid arthritis. Interference with GLUT1 using either genetic deletion or small molecules seems promising in different autoimmune mouse models and highlights the therapeutic potential of immunometabolism.
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Parijat Sarkar, Amitabha Chattopadhyay
Published Online: Feb 07 2020
DOI: 10.1002/wsbm.1481
Cholesterol binding/interaction motifs in GPCRs.
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